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UW-Madison Professor Emeritus Receives the Bayh-Dole Coalition’s American Innovator Award

A longtime professor, researcher, and science enthusiast, Jim Dahlberg was simply following his curiosity in the lab when he stumbled upon a novel enzyme that cut specific shapes of DNA.

His chance discovery turned out to be groundbreaking: the enzyme could be used in diagnostic tests to identify and isolate disease-causing cells. Today, the technology is used to detect HPV, cystic fibrosis, certain cancers, and more — giving millions of patients a better shot at early treatment and recovery. In fact, Jim’s discovery was used by Cologuard to develop their at-home colon cancer test which has screened more than 19 million people.

Jim’s work also ignited a biotech movement in Madison, changing the way university research is brought to market. When WARF took a chance on licensing his patent to the start-up Third Wave, which Jim cofounded, it paved the way for more than 100 UW spinouts and helped establish Madison as a national biotech hub.

Jim is one of five innovators profiled in the Bayh-Dole Coalition’s 2025 Faces of American Innovation report, who will receive the third annual American Innovator Award in Washington, DC, on June 4.

More Alumni Notes

Jeff Maskalunas ’18, MS’20 started ultimate frisbee programing at local Boys & Girls Clubs in the Capital Region, New York, two years ago. He recently won a grant through the USA Ultimate Foundation to continue this volunteer work.

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